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Metformin also has the ability to help avoid a blood clot, possessing properties that help avoid a hardening of the arteries that can in turn lead to a heart attack.

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Metformin stimulates ovulation in women with PCOS and can encourage regular periodseven if you don’t have diabetesIt does this by lowering insulin and blood sugar levelsPCOS can’t be cured but the symptoms can be managed.

Tell your doctor if you have recently had any of the following conditionsor if you develop them during treatmentserious infectionsevere diarrheavomitingor feveror if you drink much less fluid than usual for any reasonYou may have to stop taking metformin until you recover.

If you find you can’t tolerate the side effects of standard-release metforminyour doctor may suggest switching to slow-release tablets.

Karelaalso called bitter gourdis used to flavour foods including curries such as bitter gourd masalaIt has a bitter taste and is also made into juice and tea.

Over timepeople who have diabetes and high blood sugar can develop serious or life-threatening complicationsincluding heart diseasestrokekidney problemsnerve damageand eye problemsTaking medication(smaking lifestyle changese.gdietexercisequitting smokingand regularly checking your blood sugar may help to manage your diabetes and improve your healthThis therapy may also decrease your chances of having a heart attackstrokeor other diabetes-related complications such as kidney failurenerve damagenumbcold legs or feetdecreased sexual ability in men and womeneye problemsincluding changes or loss of visionor gum diseaseYour doctor and other healthcare providers will talk to you about the best way to manage your diabetes.

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here we report that the biguanide metformin prevents brca1 haploinsufficiency-driven rankl gene overexpression, thereby disrupting an auto-regulatory feedback control of rankl-addicted cancer stem cell-like states within brca1mut – cell populations.

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